Stress in intestine influences chromosome inheritance: Study
Cologne [Germany], February 6 : In order for the preservation of all species, inheriting a normal and intact number of chromosomes in germ cells, egg and sperm, is essential. With increasing age, the risk of the egg cell not inheriting the normal set of chromosomes increases.
The study has been published in the article titled, 'Somatic PMK-1/p38 signaling links environmental stress to germ cell apoptosis and heritable euploidy' in 'Nature Communications'.
This resulted in so-called aneuploidy, which can mean either too many or too few chromosomes. The best-known example is trisomy, also known as Down syndrome in humans. Researchers at the Institute for Genome Stability in Aging and Disease, part of the CECAD Cluster of Excellence for Aging Research at the University of Cologne, uncovered that signal from intestinal cells significantly influence the decision whether damaged eggs are eliminated or not in the nematode C. elegans.
( Details and picture courtesy ANI, the content is auto-generated from the feed.)
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